Permatex® Threadlockers fixture in approximately 20 minutes and are fully cured within 24 hours. Permatex® Surface Prep™ activator reduces fixture time to 5 minutes. Preceding values are for 3/8"-16 steel "as received" nuts and bolts at 72degF (22degC). Common applications: machine tools and presses, pumps and compressors, mounting bolts and gear boxes. For Use Where Disassembly is Common Keeps Threaded Fasteners From Vibration Loosening Ideal for 1/4" to 3/4" Fasteners (6 to 20mm) Removable with Hand Tools